Details of Metabolite

General Information of MET (ID: META00733)
Name Cholest-5-en-3beta-yl octadecanoate
Synonyms   Click to Show/Hide Synonyms of This Metabolite
18:0 Cholesteryl ester; 3beta-Octadecanoyloxycholest-5-ene; CE(18:0); Cholest-5-en-3-b-yl octadecanoate; Cholest-5-en-3-b-yl octadecanoic acid; Cholest-5-en-3-b-yl stearate; Cholest-5-en-3-b-yl stearic acid; Cholest-5-en-3-beta-yl octadecanoate; Cholest-5-en-3-beta-yl stearate; Cholest-5-en-3b-yl octadecanoate; Cholest-5-en-3b-yl octadecanoic acid; Cholest-5-en-3b-yl stearate; Cholest-5-en-3b-yl stearic acid; Cholest-5-en-3beta-yl octadecanoate; Cholest-5-en-3beta-yl stearate; Cholesterol stearate; Cholesterol stearic acid; Cholesteryl octadecanoate; Cholesteryl octadecanoic acid; Cholesteryl stearic acid; Cholestryl stearate; Cholestryl stearic acid
Source Endogenous;Sterol lipids;Cosmetic
Structure Type   Steroid esters  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Steroids and steroid derivatives
Steroid esters
PubChem CID
118246
HMDB ID
HMDB0062461
Formula
C45H80O2
Structure
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3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
ChEBI ID
82750
Physicochemical Properties Molecular Weight 653.1 Topological Polar Surface Area 26.3
XlogP 17.5 Complexity 934
Heavy Atom Count 47 Rotatable Bond Count 23
Hydrogen Bond Donor Count N.A. Hydrogen Bond Acceptor Count 2
Function
cholest-5-en-3beta-yl octadecanoate, also known as Cholest-5-en-3-b-yl stearic acid or 3beta-Octadecanoyloxycholest-5-ene, is classified as a member of the Cholesteryl esters. Cholesteryl esters are compounds containing an esterified cholestane moiety. cholest-5-en-3beta-yl octadecanoate is considered to be practically insoluble (in water) and basic. cholest-5-en-3beta-yl octadecanoate is a sterol lipid molecule
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Sulfatase sulf-1 (SULF1) Click to Show/Hide the Full List of Regulating Pair(s):   2 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair (1) Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (shRNA) of SULF1
                      Induced Change Cholest-5-en-3beta-yl octadecanoate concentration: decrease (FC = 0.32 / 0.61)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Ovarian cancer [ICD-11: 2C73]
                      Details It is reported that knockdown of SULF1 leads to the decrease of cholest-5-en-3beta-yl octadecanoate levels compared with control group.
               Regulating Pair (2) Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (shRNA) of SULF1
                      Induced Change Cholest-5-en-3beta-yl octadecanoate concentration: increase (FC = 1.72)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Ovarian cancer [ICD-11: 2C73]
                      Details It is reported that knockdown of SULF1 leads to the increase of cholest-5-en-3beta-yl octadecanoate levels compared with control group.
References
1 Erratum to: Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer. Cancer Metab. 2014 Nov 4;2:24.

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