| Regulating Pair |
| Introduced Variation |
Overexpression of Ppargc1a |
Protein Info
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| Induced Change |
Glutamic acid concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-glutamic acid concentration after Ppargc1a overexpression through HPLC based metabolomics. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
N.A. |
Skeletal muscle |
| Subcellular Location |
Nucleus (PML body) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that overexpression of Ppargc1a leads to the increase of glutamic acid levels compared with control group. |
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| References |
| 1 |
PGC-1-mediated branched-chain amino acid metabolism in the skeletal muscle. PLoS One. 2014 Mar 17;9(3):e91006.
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