| Regulating Pair |
| Introduced Variation |
Knockout of Amacr |
Protein Info
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| Induced Change |
Creatinine concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of creatinine concentration after Amacr knockout through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
N.A. |
Serum |
| Subcellular Location |
Peroxisome; Mitochondrion |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that knockout of Amacr leads to the increase of creatinine levels compared with control group. |
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| References |
| 1 |
Phytol is lethal for Amacr-deficient mice. Biochim Biophys Acta. 2015 Oct;1851(10):1394-405.
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