| Regulating Pair |
| Introduced Variation |
Overexperisson of YRDC |
Protein Info
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| Induced Change |
4-Phenylpyridine concentration: decrease |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of 4-phenylpyridine concentration after SLC22A2 and IRIP co-overexperisson through kit detection. |
| Disease Status |
Basal cell carcinoma |
ICD-11: 2C32 |
| Organ/Tissue/Cell Line |
HEK293 cells (Human embryonic kidney cells) |
Kidney |
| Subcellular Location |
Mitochondrion; Membrane |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that co-overexperisson of SLC22A2 and IRIP leads to the decrease of 4-phenylpyridine levels compared with control group in HEK293 cells. |
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| References |
| 1 |
IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity. Mol Cell Biol. 2005 Aug;25(15):6496-508.
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