| Regulating Pair |
| Introduced Variation |
Knockdown (siRNA) of SLC2A1 |
Protein Info
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| Induced Change |
Fructose concentration: decrease (FC = 0.65) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of D-fructose concentration after SLC2A1 knockdown through kit detection. |
| Disease Status |
Insulin-resistance syndromes |
ICD-11: 5A44 |
| Organ/Tissue/Cell Line |
HUVEC cells (Human Umbilical Vein Endothelial cells) |
Umbilical cord |
| Subcellular Location |
Membrane (Cell membrane); Melanosome |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that knockdown of SLC2A1 leads to the decrease of fructose levels compared with control group in HUVEC cells. |
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| References |
| 1 |
Transendothelial glucose transport is not restricted by extracellular hyperglycaemia. Vascul Pharmacol. 2016 Dec;87:219-229.
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