| Regulating Pair |
| Introduced Variation |
Overexpression of SLC38A6 |
Protein Info
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| Induced Change |
Glutamic acid concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-glutamic acid concentration after SLC38A6 overexpression through tritium Labeled amino acids kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
PC12 cells (Pheochromocytoma cells) |
Adrenal medulla |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC38A6 leads to the increase of glutamic acid levels compared with control group in PC12 cells. |
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| References |
| 1 |
Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle. Int J Mol Sci. 2021 Jan 25;22(3):1167.
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