Details of Metabolite
Full List of Protein(s) Regulating This Metabolite | ||||||
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Apolipoprotein (Apo) | ||||||
Apolipoprotein A-II (APOA2) | Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s) | |||||
Detailed Information |
Protein Info
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Regulating Pair |
Experim Info
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[1] | ||||
Introduced Variation | Mutation (-265T >C(rs5082)) of APOA2 | |||||
Induced Change | N-Acetylputrescine concentration: decrease (FC = 0.69) | |||||
Summary | Introduced Variation
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Disease Status | Obesity [ICD-11: 5B81] | |||||
Details | It is reported that mutation (-265T >C(rs5082)) of APOA2 leads to the decrease of N-acetylputrescine levels compared with control group. | |||||
Hydrolases (EC 3) | ||||||
GTPase KRas (KRAS) | Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s) | |||||
Detailed Information |
Protein Info
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Regulating Pair |
Experim Info
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[2] | ||||
Introduced Variation | Overexpression of KRAS | |||||
Induced Change | N-Acetylputrescine concentration: decrease (FC = 0.32) | |||||
Summary | Introduced Variation
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Disease Status | Lung cancer [ICD-11: 2C25] | |||||
Details | It is reported that overexpression of KRAS leads to the decrease of N-acetylputrescine levels compared with control group. | |||||
Sulfatase sulf-1 (SULF1) | Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s) | |||||
Detailed Information |
Protein Info
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Regulating Pair |
Experim Info
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[3] | ||||
Introduced Variation | Knockdown (shRNA) of SULF1 | |||||
Induced Change | N-Acetylputrescine concentration: decrease (FC = 0.08 / 0.13) | |||||
Summary | Introduced Variation
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Disease Status | Ovarian cancer [ICD-11: 2C73] | |||||
Details | It is reported that knockdown of SULF1 leads to the decrease of N-acetylputrescine levels compared with control group. | |||||
Pore-forming PNC peptide (PNC) | ||||||
Cellular tumor antigen p53 (TP53) | Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s) | |||||
Detailed Information |
Protein Info
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Regulating Pair |
Experim Info
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[4] | ||||
Introduced Variation | Knockout of TP53 | |||||
Induced Change | N-Acetylputrescine concentration: decrease (Log2 FC=0.72) | |||||
Summary | Introduced Variation
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Disease Status | Colon cancer [ICD-11: 2B90] | |||||
Details | It is reported that knockout of TP53 leads to the decrease of N-acetylputrescine levels compared with control group. | |||||
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