Details of Protein

General Information of Protein (ID: PRT00665)
Name G-protein coupled receptor 34 (GPR34)
Synonyms   Click to Show/Hide Synonyms of This Protein
Gpr34
Gene Name Gpr34 Gene ID
23890
UniProt ID
Q9R1K6
Family GPCR rhodopsin (GPCR-1)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MTTTSVDSWLCSSHGMHFITNYSDQASQNFSGVPNVTSCPMDEKLLSTVLTTFYSVIFLV
GLVGNIIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNKWTLGVILC
KVVGTLFYMNMYISIILLGFISLDRYIKINRSIQQRRAITTKQSIYVCCIVWTVALAGFL
TMIILTLKKGGHNSTMCFHYRDRHNAKGEAIFNFVLVVMFWLIFLLIILSYIKIGKNLLR
ISKRRSKFPNSGKYATTARNSFIVLIIFTICFVPYHAFRFIYISSQLNVSSCYWKEIIHK
TNEIMLVFSSFNSCLDPVMYFLMSSNIRKIMCQLLFRRFQSEASRSESTSEFKPGHSLHD
LSVTVKMPQYSTKGN
Function Orphan receptor.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Lipids and lipid-like molecules
            LysoPS(18:0/0:0) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation LysoPS(18:0/0:0) addition (4 hours)
                      Induced Change GPR34 protein activity levels: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Anaphylaxis [ICD-11: 4A84]
                      Details It is reported that lysoPS(18:0/0:0) addition causes the increase of GPR34 protein activity compared with control group.
References
1 Identification of a lysophosphatidylserine receptor on mast cells. Biochem Biophys Res Commun. 2006 Mar 24;341(4):1078-87.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.