| Regulating Pair |
| Introduced Variation |
LysoPS(18:0/0:0) addition (4 hours) |
Metabo Info
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| Induced Change |
GPR34 protein activity levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of GPR34 protein activity abundances after lysophosphatidylserine addition through assay of degranulation analysis. |
| Disease Status |
Anaphylaxis |
ICD-11: 4A84 |
| Organ/Tissue/Cell Line |
LAD 2 cells (Human mast cells) |
Bone marrow |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that lysoPS(18:0/0:0) addition causes the increase of GPR34 protein activity compared with control group in the LAD 2 cells. |
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| References |
| 1 |
Identification of a lysophosphatidylserine receptor on mast cells. Biochem Biophys Res Commun. 2006 Mar 24;341(4):1078-87.
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