| Regulating Pair |
| Introduced Variation |
Knockout of Drd4 |
Protein Info
|
| Induced Change |
Homovanillic acid concentration: decrease (FC = 0.60) |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of homovanillic acid concentration after DRD4 knockout through kit detection. |
| Disease Status |
Healthy individual |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
|
| Details |
It is reported that knockout of DRD4 leads to the decrease of homovanillic acid levels compared with control group. |
|
|
|
|
|
|
|
| References |
| 1 |
Dopamine D4 receptor knockout mice exhibit neurochemical changes consistent with decreased dopamine release. J Neurosci Methods. 2007 Nov 30;166(2):306-14.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
