| Regulating Pair |
| Introduced Variation |
Knockout of Mocs1 |
Protein Info
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| Induced Change |
Cysteine-S-sulfate concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of cysteine-S-sulfate concentration after Mocs1 knockout through Reversed-phase HPLC based metabolomics. |
| Disease Status |
Organic acid disorderss |
ICD-11: 5C50 |
| Organ/Tissue/Cell Line |
N.A. |
Blood Plasma Of Embryos |
| Subcellular Location |
Cytoplasm (Cytosol) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that knockout of Mocs1 leads to the increase of cysteine-S-sulfate levels compared with control group. |
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| References |
| 1 |
The pathogenesis of molybdenum cofactor deficiency, its delay by maternal clearance, and its expression pattern in microarray analysis. Mol Genet Metab. 2005 May;85(1):12-20.
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