Regulating Pair
       Introduced Variation Recombinant protein addition of SLC15A3 Protein Info
       Induced Change Histidine concentration: decrease Metabo Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the change of L-histidine concentration after SLC15A3 recombinant protein addition through 14C-labeled amino acids kit detection.
       Disease Status Healthy individual
       Subcellular Location Lysosome (Lysosome membrane); Endosome (Endosome membrane)
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that recombinant protein addition of SLC15A3 leads to the decrease of histidine levels compared with control group.
References
1 Cloning of a lymphatic peptide/histidine transporter. Biochem J. 2001 May 15;356(Pt 1):53-60.

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