| Regulating Pair |
| Introduced Variation |
Mutation (GLUT3+/-) of Slc2a3 |
Protein Info
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| Induced Change |
Cholesterol concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of cholesterol concentration after Slc2a3 mutation (GLUT3+/-) through Colorimetric assay. |
| Disease Status |
Healthy individual |
| Subcellular Location |
Membrane (Cell membrane); Cytoplasm (Perikaryon); Cell projection |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that mutation (GLUT3+/-) of Slc2a3 leads to the increase of cholesterol levels compared with control group. |
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| References |
| 1 |
Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance. Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1144-51.
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