| Regulating Pair |
| Introduced Variation |
Recombinant protein addition of SLC25A36 |
Protein Info
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| Induced Change |
2'-Deoxyguanosine 5'-monophosphate concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of 2'-deoxyguanosine 5'-monophosphate concentration after SLC25A36 recombinant protein addition through Sephadex G-75 columns based metabolomics. |
| Disease Status |
Healthy individual |
| Subcellular Location |
Mitochondrion (Mitochondrion inner membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that recombinant protein addition of SLC25A36 leads to the increase of 2'-deoxyguanosine 5'-monophosphate levels compared with control group. |
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| References |
| 1 |
The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem. 2014 Nov 28;289(48):33137-48.
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