Regulating Pair
       Introduced Variation Knockout of Aloxe3 Protein Info
       Induced Change Trioxilin A3 concentration: decrease Metabo Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the change of trioxilin A3 concentration after Aloxe3 knockout through HPLC-MS/MS based metabolomics.
       Disease Status Healthy individual
       Subcellular Location Cytoplasm
       Tested Species   Species: Mus musculus  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
       Details It is reported that knockout of Aloxe3 leads to the decrease of trioxilin A3 levels compared with control group.
References
1 Aloxe3 knockout mice reveal a function of epidermal lipoxygenase-3 as hepoxilin synthase and its pivotal role in barrier formation. J Invest Dermatol. 2013 Jan;133(1):172-80.

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