| Regulating Pair |
| Introduced Variation |
Knockdown (shRNA) of Slc17a9 |
Protein Info
|
| Induced Change |
ATP concentration: decrease |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of adenosine triphosphate concentration after Slc17a9 knockdown through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
C2C12 cells (Mouse skeletal muscle cells) |
Muscle |
| Subcellular Location |
Membrane |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
|
| Details |
It is reported that knockdown of Slc17a9 leads to the decrease of ATP levels compared with control group in C2C12 cells. |
|
|
|
|
|
|
|
| References |
| 1 |
SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viability. J Biol Chem. 2014 Aug 15;289(33):23189-23199.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
