| Regulating Pair |
| Introduced Variation |
Overexpression of SLCO1C1 |
Protein Info
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| Induced Change |
Liothyronine concentration: increase (FC = 14) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of liothyronine concentration after SLCO1C1 overexpression through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
CHO cells (Chinese hamster ovary cells) |
N.A. |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLCO1C1 leads to the increase of liothyronine levels compared with control group in CHO cells. |
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| References |
| 1 |
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter. Mol Endocrinol. 2002 Oct;16(10):2283-96.
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