| Regulating Pair |
| Introduced Variation |
Overexpression of SLC37A4 |
Protein Info
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| Induced Change |
Glucose 6-phosphate concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of glucose 6-phosphate concentration after SLC37A4 overexpression through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
COS-1 cells (Transformed african green monkey kidney fibroblast cells) |
Kidney |
| Subcellular Location |
Endoplasmic reticulum (Endoplasmic reticulum membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC37A4 leads to the increase of glucose 6-phosphate levels compared with control group in COS-1 cells. |
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| References |
| 1 |
SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters. PLoS One. 2011;6(9):e23157.
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