| Regulating Pair |
| Introduced Variation |
Overexpression of SLC35F3 |
Protein Info
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| Induced Change |
Thiamine concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of thiamine concentration after SLC35F3 overexpression through [3H]labeled amino acids kit detection. |
| Disease Status |
Essential hypertension |
ICD-11: BA00 |
| Organ/Tissue/Cell Line |
E. coli |
N.A. |
| Subcellular Location |
Membrane |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC35F3 leads to the increase of thiamine levels compared with control group in coli. E. coli. |
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| References |
| 1 |
Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22;63(15):1542-55.
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