| Regulating Pair |
| Introduced Variation |
Overexpression of SLC2A11 |
Protein Info
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| Induced Change |
Glucose concentration: increase (FC = 2.5) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of D-glucose concentration after SLC2A11 overexpression through 3H- or 14C-labeled amino acids assay. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HEK293 cells (Human embryonic kidney cells) |
Kidney |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC2A11 leads to the increase of glucose levels compared with control group in HEK293 cells. |
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| References |
| 1 |
Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues. Mol Genet Metab. 2002 May;76(1):37-45.
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