| Regulating Pair |
| Introduced Variation |
Overexpression of SLC19A3 |
Protein Info
|
| Induced Change |
Thiamine concentration: increase (FC = 3.5) |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of thiamine concentration after SLC19A3 overexpression through 3H-labeled amino acids kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HeLa cells (Human cervical cancer cells) |
Cervix |
| Subcellular Location |
Membrane |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that overexpression of SLC19A3 leads to the increase of thiamine levels compared with control group in HeLa cells. |
|
|
|
|
|
|
|
| References |
| 1 |
SLC19A3 encodes a second thiamine transporter ThTr2. Biochim Biophys Acta. 2001 Nov 29;1537(3):175-8.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
