| Regulating Pair |
| Introduced Variation |
Overexpression of SLC23A2 |
Protein Info
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| Induced Change |
Ascorbic acid concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of ascorbic acid concentration after SLC23A2 overexpression through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HRPE cells (Adult retinal pigment epithelial) |
Retina |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC23A2 leads to the increase of ascorbic acid levels compared with control group in HRPE cells. |
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| References |
| 1 |
Human placental sodium-dependent vitamin C transporter (SVCT2): molecular cloning and transport function. Biochem Biophys Res Commun. 1999 Sep 7;262(3):762-8.
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