| Regulating Pair |
| Introduced Variation |
Knockdown (siRNA) of Slc17a9 |
Protein Info
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| Induced Change |
ATP concentration: decrease (FC = 0.50) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of adenosine triphosphate concentration after Slc17a9 knockdown through kit detection. |
| Disease Status |
Adrenomedullary hyperfunction |
ICD-11: 5A75 |
| Organ/Tissue/Cell Line |
PC12 cells (Pheochromocytoma cells) |
Adrenal medulla |
| Subcellular Location |
Membrane |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that knockdown of Slc17a9 leads to the decrease of ATP levels compared with control group in PC12 cells. |
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| References |
| 1 |
Identification of a vesicular nucleotide transporter. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5683-6.
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