| Regulating Pair |
| Introduced Variation |
Knockout of Cth |
Protein Info
|
| Induced Change |
D-Aspartic acid concentration: increase (FC = 2.10) |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of D-aspartic acid concentration after Cth knockout through LC/MS/MS (using negative ion model) based metabolomics. |
| Disease Status |
Organic acid disorderss |
ICD-11: 5C50 |
| Organ/Tissue/Cell Line |
Red blood cells |
Blood |
| Subcellular Location |
Cytoplasm |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
|
| Details |
It is reported that knockout of Cth leads to the increase of D-aspartic acid levels compared with control group in red blood cells. |
|
|
|
|
|
|
|
| References |
| 1 |
Hydrogen Sulfide Is a Regulator of Hemoglobin Oxygen-Carrying Capacity via Controlling 2,3-BPG Production in Erythrocytes. Oxid Med Cell Longev. 2021 Feb 13;2021:8877691.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
