Regulating Pair
       Introduced Variation Overexpression of Slc7a2 Protein Info
       Induced Change Arginine concentration: increase (FC = 12 - 20) Metabo Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the change of L-arginine concentration after Slc7a2 overexpression through [3H]labeled amino acids kit detection.
       Disease Status Healthy individual
       Organ/Tissue/Cell Line Xenopus laevis oocytes N.A.
       Subcellular Location Membrane (Cell membrane)
       Tested Species   Species: Mus musculus  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
       Details It is reported that overexpression of Slc7a2 leads to the increase of arginine levels compared with control group in xenopus laevis oocytes.
References
1 Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry. 1997 May 27;36(21):6462-8.

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