Regulating Pair |
Introduced Variation |
Overexpression of SLC29A2 |
Protein Info
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Induced Change |
Adenosine concentration: increase |
Metabo Info
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Summary |
Introduced Variation
Induced Change
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Full List of Experiment(s) Validating This Regulating Pair |
Details of Experiment for Validating This Pair |
[1] |
Method |
Quantifying the change of adenosine concentration after SLC29A2 overexpression through C14-labeled amino acids kit detection. |
Disease Status |
Healthy individual |
Organ/Tissue/Cell Line |
Xenopus oocytes |
N.A. |
Subcellular Location |
Membrane (Cell membrane; Basolateral Membrane); Nucleus membrane |
Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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Details |
It is reported that overexpression of SLC29A2 leads to the increase of adenosine levels compared with control group in xenopus oocytes. |
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References |
1 |
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem J. 1997 Dec 15;328 ( Pt 3)(Pt 3):739-43.
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