| Regulating Pair |
| Introduced Variation |
Mutation (RRR4/6AAA+YIRV599/602AIRA) of Slc2a13 |
Protein Info
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| Induced Change |
myo-Inositol concentration: increase (FC = 6) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of myo-inositol concentration after Slc2a13 mutation (RRR4/6AAA+YIRV599/602AIRA) through kit detection |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
Xenopus oocytes |
N.A. |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Rattus norvegicus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Rattus
Species: Rattus norvegicus
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| Details |
It is reported that mutation (RRR4/6AAA+YIRV599/602AIRA) of Slc2a13 leads to the increase of myo-inositol levels compared with control group in xenopus oocytes. |
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| References |
| 1 |
Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain. EMBO J. 2001 Aug 15;20(16):4467-77.
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