| Regulating Pair |
| Introduced Variation |
Methionine addition (336 hours) |
Metabo Info
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| Induced Change |
PSME1 protein expression levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of PSME1 protein abundances after methionine addition through two-dimensional (2-D) DIGE analysis. |
| Disease Status |
Hyperhomocysteinaemia |
ICD-11: 3B61 |
| Organ/Tissue/Cell Line |
N.A. |
Liver |
| Subcellular Location |
Nucleoplasm; Cytoplasm |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that methionine addition causes the increase of PSME1 protein expression compared with control group in the mouse liver. |
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| References |
| 1 |
The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia. Mol Cell Proteomics. 2010 Mar;9(3):471-85.
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