Details of Experiment

Regulating Pair
Introduced Variation	Glutamine addition (12 hours)	Metabo Info
Induced Change	UBE2V2 protein expression levels: decrease	Protein Info
Summary	Introduced Variation Induced Change

Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair			[1]
Method	Quantifying the variation of UBE2V2 protein abundances after glutamine addition through 2-D quant kit analysis.
Disease Status	Inflammatory bowel disease	ICD-11: DD72
Organ/Tissue/Cell Line	HCT-8 cells (Human colon tumor cells)	Intestinal epithelium
Subcellular Location	Cytoplasm (Extracellular exosome); Nucleus (Nucleoplasm)
Tested Species	Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage) Kingdom: Metazoa Phylum: Chordata Class: Mammalia Order: Primates Family: Hominidae Genus: Homo Species: Homo sapiens
Details	It is reported that glutamine addition causes the decrease of UBE2V2 protein expression compared with control group in the HCT-8 cells under proinflammatory conditions.

References
1	Proteomic analysis of glutamine-treated human intestinal epithelial HCT-8 cells under basal and inflammatory conditions. Proteomics. 2006 Jul;6(13):3926-37.

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