| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment (1) for Validating Pair |
[1] |
| Method |
Quantifying the variation of MAPK1 protein phosphorylation abundances after 1-oleoyl-Lysophosphatidic acid addition through western blot analysis. |
| Disease Status |
Systemic sclerosis |
ICD-11: 4A42 |
| Organ/Tissue/Cell Line |
HDF (Human dermal fibroblasts) |
Dermis |
| Subcellular Location |
Cytoplasm (Cytoskeleton; Spindle); Nucleus; Centrosome; Cytoplasm; Membrane (caveola) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that lysoPA(18:1(9Z)/0:0) addition causes the increase of MAPK1 protein phosphorylation compared with control group in the HDF cells. |
| Details of Experiment (2) for Validating Pair |
[1] |
| Method |
Quantifying the variation of MAPK1 protein phosphorylation abundances after 1-oleoyl-Lysophosphatidic acid addition through western blot analysis. |
| Disease Status |
Idiopathic pulmonary fibrosis |
ICD-11: CB03 |
| Organ/Tissue/Cell Line |
HLF (Human lung fibroblasts) |
Lung |
| Subcellular Location |
Cytoplasm (Cytoskeleton; Spindle); Nucleus; Centrosome; Cytoplasm; Membrane (caveola) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that lysoPA(18:1(9Z)/0:0) addition causes the increase of MAPK1 protein phosphorylation compared with control group in the HLF cells. |
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Induced Change