| Regulating Pair |
| Introduced Variation |
Glutamine addition (24 hours) |
Metabo Info
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| Induced Change |
MAP1LC3B protein expression levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of MAP1LC3B protein abundances after glutamine addition through western blot analysis. |
| Disease Status |
Sepsis |
ICD-11: 1G40 |
| Organ/Tissue/Cell Line |
IEC-18 cells (Rat intestinal epithelial cells) |
Intestinal epithelium |
| Subcellular Location |
Cytoplasm (Cytoskeleton); Membrane (Endomembrane system; Cytoplasmic vesicle; Autophagosome membrane) |
| Tested Species |
Species: Rattus norvegicus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Rattus
Species: Rattus norvegicus
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| Details |
It is reported that glutamine addition causes the increase of MAP1LC3B protein expression compared with control group in the rat intestinal Epithelial Iec18 cells. |
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| References |
| 1 |
Glutamine increases autophagy under Basal and stressed conditions in intestinal epithelial cells. Gastroenterology. 2009 Mar;136(3):924-32.
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