| Regulating Pair |
| Introduced Variation |
Leucine decrease (2 hours) |
Metabo Info
|
| Induced Change |
PDIA3 protein phosphorylation levels: increase |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of PDIA3 protein phosphorylation abundances after leucine decrease through 2DPAGE analysis. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
C2C12 cells (Mouse myoblasts) |
Muscle |
| Subcellular Location |
Endoplasmic reticulum (Endoplasmic reticulum lumen); Melanosome |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
|
| Details |
It is reported that leucine decrease causes the increase of PDIA3 protein phosphorylation compared with control group in the C2C12 myoblasts. |
|
|
|
|
|
|
|
| References |
| 1 |
Phospho-proteomic approach to identify new targets of leucine deprivation in muscle cells. Anal Biochem. 2008 Oct 1;381(1):148-50.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
