Regulating Pair |
Introduced Variation |
Leucine addition (1.50 hours) |
Metabo Info
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Induced Change |
UCP3 protein expression levels: increase (FC = 0.01227) |
Protein Info
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Summary |
Introduced Variation
Induced Change
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Full List of Experiment(s) Validating This Regulating Pair |
Details of Experiment for Validating This Pair |
[1] |
Method |
Quantifying the variation of UCP3 protein abundances after leucine addition through immunoblotting analysis. |
Disease Status |
Healthy individual |
Organ/Tissue/Cell Line |
N.A. |
Skeletal muscle |
N.A. |
Brown adipose tissue |
N.A. |
White adipose tissue |
Subcellular Location |
Mitochondrion (Mitochondrion inner membrane) |
Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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Details |
It is reported that leucine addition causes the increase of UCP3 protein expression compared with control group in the C57BL/6J mice. |
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References |
1 |
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms. Diabetes. 2007 Jun;56(6):1647-54.
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