| Regulating Pair |
| Introduced Variation |
Arginine decrease (24 hours) |
Metabo Info
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| Induced Change |
CD247 mRNAlevel levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of CD247 mRNA levels abundances after arginine decrease through northern blot analysis. |
| Disease Status |
Sepsis |
ICD-11: 1G40 |
| Organ/Tissue/Cell Line |
Jurkat T cells |
Blood |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that arginine decrease causes the decrease of CD247 mRNA levels compared with control group in the jurkat T cells. |
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| References |
| 1 |
Regulation of T cell receptor CD3zeta chain expression by L-arginine. J Biol Chem. 2002 Jun 14;277(24):21123-9.
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