| Regulating Pair |
| Introduced Variation |
N-Arachidonoylglycine addition (24 hours) |
Metabo Info
|
| Induced Change |
LPAR5 protein activity levels: increase |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of LPAR5 protein activity abundances after N-arachidonoylglycine addition through measurement of intracellular Ca2+ mobilization analysis. |
| Disease Status |
Hepatocellular carcinoma |
ICD-11: 2C12 |
| Organ/Tissue/Cell Line |
Rh7777 cells (McArtl hepatoma cells) |
Liver |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that N-arachidonoylglycine addition causes the increase of LPAR5 protein activity compared with control group in the Rh7777 cells. |
|
|
|
|
|
|
|
| References |
| 1 |
Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. J Biol Chem. 2009 Jun 19;284(25):17304-17319.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
