| Regulating Pair |
| Introduced Variation |
Glucose addition (16 hours) |
Metabo Info
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| Induced Change |
GPR84 mRNA levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of GPR84 mRNA levels abundances after D-glucose addition through quantitative real-time RT-PCR analysis. |
| Disease Status |
Diabetes mellitus |
ICD-11: 5A14 |
| Organ/Tissue/Cell Line |
BMDMs (Bone marrow-derived macrophages) |
Bone marrow |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that glucose addition causes the increase of GPR84 mRNA levels compared with control group in the bone marrow-derived macrophages cells. |
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| References |
| 1 |
Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Front Immunol. 2018 Jun 20;9:1419.
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