| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of GPR183 protein activity abundances after 7alpha-hydroxycholesterol addition through GTPS binding assay analysis or cAMP accumulation assay analysis. |
| Disease Status |
Systemic inflammatory response syndrome |
ICD-11: 1H0Z |
| Organ/Tissue/Cell Line |
CHO-k1 cells (Chinese hamster ovary cells) |
Ovary |
| SK-N-MC cells (Human neuroepithelioma adherent cells) |
Brain |
| Cre--galactosidase cells |
Brain |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that 7-alpha-hydroxycholesterol addition causes the increase of GPR183 protein activity compared with control group in the CHO-k1 cells, SK-N-MC cells amd Cre--galactosidase cells. |
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Induced Change