| Regulating Pair |
| Introduced Variation |
LysoPS(18:0/0:0) addition (24 hours) |
Metabo Info
|
| Induced Change |
GPR174 protein activity levels: increase |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of GPR174 protein activity abundances after lysophosphatidylserine addition through TGF shedding assay analysis. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HEK 293 cells (Human embryonic kidney cells) |
Kidney |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that lysoPS(18:0/0:0) addition causes the increase of GPR174 protein activity compared with control group in the HEK293 cells. |
|
|
|
|
|
|
|
| References |
| 1 |
TGF shedding assay: an accurate and versatile method for detecting GPCR activation. Nat Methods. 2012 Oct;9(10):1021-9.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
