| Regulating Pair |
| Introduced Variation |
N-Arachidonoylglycine addition (0.08 hours) |
Metabo Info
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| Induced Change |
MAPK3 protein phosphorylation levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of MAPK3 protein phosphorylation abundances after N-arachidonoylglycine addition through western blot analysis. |
| Disease Status |
Endometriosis |
ICD-11: GA10 |
| Organ/Tissue/Cell Line |
HEK293/GPR18 cells (Human embryonic kidney cells expressing GPR18) |
Kidney |
| Subcellular Location |
Cytoplasm; Nucleus; Membrane (Caveola) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that N-arachidonoylglycine addition causes the increase of MAPK3 protein phosphorylation compared with control group in the HEK293GPR18 cells. |
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| References |
| 1 |
(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. Br J Pharmacol. 2012 Apr;165(8):2414-24.
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