Details of Experiment

Regulating Pair
       Introduced Variation Glucose addition (50 hours) Metabo Info
       Induced Change MAPK3 protein abundance levels: increase Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of MAPK3 protein abundances after glucose addition through western blot analysis.
       Disease Status Brain cancer ICD-11: 2A00
       Organ/Tissue/Cell Line U87-EGFRvIII cells (Human glioma cells expressing EGFRvIII) Brain
U87 cells (Human glioma cells) Brain
       Subcellular Location Cytoplasm; Nucleus; Membrane (Caveola)
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that glucose addition causes the increase of MAPK3 protein abundance compared with control group in the U87-EGFRvIII cells and U87 cells.
References
1 Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Mol Syst Biol. 2012 Jun 26;8:589.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.