Regulating Pair
       Introduced Variation Sodium oxamate addition (3 hours) Metabo Info
       Induced Change TBK1 protein phosphorylation levels: increase Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of TBK1 protein phosphorylation abundances after sodium oxamate addition through western blot analysis.
       Disease Status Acute lymphoblastic leukemia ICD-11: 2B33
       Organ/Tissue/Cell Line Hep3B cells (Human hepatoma cells) Liver
       Subcellular Location Cytoplasm
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that sodium oxamate addition causes the increase of TBK1 protein phosphorylation compared with control group in the Hep3B cells.
References
1 Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019 Jun 27;178(1):176-189.e15.

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