| Regulating Pair |
| Introduced Variation |
Arginine decrease (24 hours) |
Metabo Info
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| Induced Change |
ASS1 protein expression levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of ASS1 protein abundances after low arginine starvation through capillary western system. |
| Disease Status |
Leiomyosarcoma |
ICD-11: 2B58 |
| Organ/Tissue/Cell Line |
SKLMS-1 cells (Leiomyosarcoma cells) |
Smooth muscle |
| Subcellular Location |
Nucleus; Cytoplasm |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that arginine decrease causes the increase of ASS1 protein expression compared with control group in SKLMS-1 cells. |
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| References |
| 1 |
Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming. Cell Death Dis. 2020 Aug 20;11(8):662.
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