| Regulating Pair |
| Introduced Variation |
Sodium oxamate addition (4 hours) |
Metabo Info
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| Induced Change |
IL6 mRNA levels: increase (FC = 3) |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of IL6 mRNA levels abundances after sodium oxamate addition through quantitative real-time RT-PCR analysis. |
| Disease Status |
Acute lymphoblastic leukemia |
ICD-11: 2B33 |
| Organ/Tissue/Cell Line |
N.A. |
Lung |
| Subcellular Location |
Secreted |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that sodium oxamate addition causes the increase of IL6 mRNA levels compared with control group in the Vsv-mouse. |
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| References |
| 1 |
Lactate Is a Natural Suppressor of RLR Signaling by Targeting MAVS. Cell. 2019 Jun 27;178(1):176-189.e15.
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