General Information of MET (ID: META01380)
Name Alpha-hydroxy-ceramides
Structure Type Lipid-related molecules
Structure
2D MOL
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Alkaline ceramidase 1 (ACER1) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of Acer1
                      Induced Change Alpha-hydroxy-ceramides concentration: increase (FC = 3.70)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that knockout of Acer1 leads to the increase of alpha-hydroxy-ceramides levels compared with control group.
References
1 Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells. Stem Cell Reports. 2017 Nov 14;9(5):1488-1500.

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