Details of Metabolite

General Information of MET (ID: META01243)
Name Kumatakenin
Synonyms   Click to Show/Hide Synonyms of This Metabolite
Kumatakenin; Jaranol; 3301-49-3; Kumatakillin; UNII-5FAQ11412T; 5,4'-dihydroxy-3,7-dimethoxyflavone; 5FAQ11412T; 4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-; 5-Hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxy-4H-chromen-4-one; 5-hydroxy-2-(4-hydroxyphenyl)-3,7-dimethoxychromen-4-one; Flavone, 4',5-dihydroxy-3,7-dimethoxy-; 3,7-Di-O-methyl kaempferol; Kaempferol 3,7-dimethyl ether; CHEMBL349724; MEGxp0_000177; SCHEMBL3351483
Source Drug;Toxins/Pollutant
Structure Type Benzenoids
PubChem CID
5318869
Formula
C17H14O6
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 314.29 Topological Polar Surface Area 85.2
XlogP 2.5 Complexity 480
Heavy Atom Count 23 Rotatable Bond Count 3
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Transcription factor (TF)
            R2R3-MYB (AN2) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Overexpression of AN2
                      Induced Change Kumatakenin concentration: decrease
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that overexpression of AN2 leads to the decrease of kumatakenin levels compared with control group.
References
1 Comprehensive Influences of Overexpression of a MYB Transcriptor Regulating Anthocyanin Biosynthesis on Transcriptome and Metabolome of Tobacco Leaves. Int J Mol Sci. 2019 Oct 16;20(20):5123.

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