Details of Metabolite

General Information of MET (ID: META01179)
Name S-Methylglutathione
Synonyms   Click to Show/Hide Synonyms of This Metabolite
S-Methylglutathione; S-Methyl glutathione; 2922-56-7; Glutathione ester; S-METHYL-GLUTATHIONE; Glutathione S-methyl ester; L-gamma-Glutamyl-S-methyl-L-cysteinylglycine; UNII-OOW3025SR1; S-Methyl GSH; OOW3025SR1; L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE; N5-((R)-1-((carboxymethyl)amino)-3-(methylthio)-1-oxopropan-2-yl)-L-glutamine; GSM; SCHEMBL1767370; CHEMBL1233129; Glycine, N-(N-L-gamma-glutamyl-S-methyl-L-cysteinyl)-; DTXSID10183479; CHEBI:141472
Structure Type   Amino acids, peptides, and analogues  (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
PubChem CID
115260
Formula
C11H19N3O6S
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 321.35 Topological Polar Surface Area 184
XlogP -4.1 Complexity 403
Heavy Atom Count 21 Rotatable Bond Count 10
Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 8
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Transcription factor (TF)
            R2R3-MYB (AN2) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Overexpression of AN2
                      Induced Change S-Methylglutathione concentration: decrease
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that overexpression of AN2 leads to the decrease of s-methylglutathione levels compared with control group.
References
1 Comprehensive Influences of Overexpression of a MYB Transcriptor Regulating Anthocyanin Biosynthesis on Transcriptome and Metabolome of Tobacco Leaves. Int J Mol Sci. 2019 Oct 16;20(20):5123.

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