Details of Metabolite

General Information of MET (ID: META00962)
Name 2-Arachidonoylglycerolphosphoinositol
Synonyms   Click to Show/Hide Synonyms of This Metabolite
2-arachidonoylglycerolphosphoinositol; arachidonoyl LPI; [3-hydroxy-2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxypropyl] (2,3,4,5,6-pentahydroxycyclohexyl) phosphate; 2-AGPI; 2-arachidonoyl-glycerol-phosphoinositol; GTPL4029; Q27071881
Source Endogenous;Sterol lipids;Food
Structure Type   Glycerophosphoinositols  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Glycerophospholipids
Glycerophosphoinositols
PubChem CID
73755068
Formula
C29H48O12P-
Structure
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3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 619.7 Topological Polar Surface Area 206
XlogP 1.4 Complexity 881
Heavy Atom Count 42 Rotatable Bond Count 22
Hydrogen Bond Donor Count 6 Hydrogen Bond Acceptor Count 12
Regulatory Network
Full List of Protein(s) Regulated by This Metabolite
      GPCR rhodopsin (GPCR-1)
            G-protein coupled receptor 55 (GPR55) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation 2-Arachidonoylglycerolphosphoinositol addition (48 hours)
                      Induced Change GPR55 protein activity levels: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that 2-arachidonoylglycerolphosphoinositol addition causes the increase of GPR55 protein activity compared with control group.
References
1 2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55. J Biochem. 2009 Jan;145(1):13-20.

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