Details of Metabolite

General Information of MET (ID: META00852)
Name Gallic acid
Synonyms   Click to Show/Hide Synonyms of This Metabolite
3,4,5-Trihydroxy-benzoate; 3,4,5-Trihydroxy-benzoic acid; 3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzoic acid; 3,4,5-Trihydroxybenzoic acid (acd/name 4.0); Acid, gallic; Gallate; Gallic acid polymer; Gallic acid tech.; Galop; Pyrogallol-5-carboxylate; Pyrogallol-5-carboxylic acid
Source Food;Drug;Escherichia Coli Metabolite;Yeast Metabolite;Food;Carcinogenic Potency;Cosmetic;TCM Ingredients;(-)-Epicatechin;3-O-gallate;Plant Metabolite; Microbial; Herbal Ingredients In-Vivo Metabolism
Structure Type   Benzoic acids and derivatives  (Click to Show/Hide the Complete Structure Type Hierarchy)
Benzenoids
Benzene and substituted derivatives
Benzoic acids and derivatives
PubChem CID
370
HMDB ID
HMDB0005807
Formula
C7H6O5
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
KEGG ID
C01424
ChEBI ID
30778
FooDB ID
FDB000662
ChemSpider ID
361
METLIN ID
3295
Physicochemical Properties Molecular Weight 170.12 Topological Polar Surface Area 98
XlogP 0.7 Complexity 169
Heavy Atom Count 12 Rotatable Bond Count 1
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 5
Function
Gallic acid is an organic acid, also known as 3,4,5-trihydroxybenzoic acid, found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. The chemical formula is C6H2(OH)3CO2H. Gallic acid is found both free and as part of tannins. It is commonly used in the pharmaceutical industry. Gallic acid can also be used to synthesize the hallucinogenic alkaloid mescaline, also known as 3,4,5-trimethoxyphenethylamine. Salts and esters of gallic acid are termed gallates. Gallic acid has been found to be s metabolite of Aspergillus.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Transcription factor (TF)
            R2R3-MYB (AN2) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Overexpression of AN2
                      Induced Change Gallic acid concentration: increase (FC = 130592.59)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that overexpression of AN2 leads to the increase of gallic acid levels compared with control group.
References
1 Comprehensive Influences of Overexpression of a MYB Transcriptor Regulating Anthocyanin Biosynthesis on Transcriptome and Metabolome of Tobacco Leaves. Int J Mol Sci. 2019 Oct 16;20(20):5123.

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