Details of Metabolite

General Information of MET (ID: META00835)
Name Myricetin
Synonyms   Click to Show/Hide Synonyms of This Metabolite
3,3',4',5,5',7-Hexahydroxyflavone, 3,5,7,3',4',5'-Hexahydroxyflavone, 'Cannabiscetin; Myricetol', 3,3',4',5,5',7-Hexahydroxy-(8ci)- flavone, '3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
Source Food;Plant;Metabolite;Yeast Metabolite;Polyketides;Food;Drug;TCM Ingredients;Myricitrin;Plant Metabolite; Microbial; Herbal Ingredients In-Vivo Metabolism
Structure Type   Flavones  (Click to Show/Hide the Complete Structure Type Hierarchy)
Phenylpropanoids and polyketides
Flavonoids
Flavones
PubChem CID
5281672
HMDB ID
HMDB0002755
Formula
C15H10O8
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
KEGG ID
C10107
DrugBank ID
DB02375
ChEBI ID
18152
FooDB ID
FDB012724
ChemSpider ID
4444991
METLIN ID
3448
Physicochemical Properties Molecular Weight 318.23 Topological Polar Surface Area 148
XlogP 1.2 Complexity 506
Heavy Atom Count 23 Rotatable Bond Count 1
Hydrogen Bond Donor Count 6 Hydrogen Bond Acceptor Count 8
Function
Myricetin is a naturally-occurring flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants. Walnuts are a rich dietary source. It has been shown that myricetin has antioxidant properties. -- Wikipedia.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Transcription factor (TF)
            R2R3-MYB (AN2) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Overexpression of AN2
                      Induced Change Myricetin concentration: increase (FC = 239185.19)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that overexpression of AN2 leads to the increase of myricetin levels compared with control group.
References
1 Comprehensive Influences of Overexpression of a MYB Transcriptor Regulating Anthocyanin Biosynthesis on Transcriptome and Metabolome of Tobacco Leaves. Int J Mol Sci. 2019 Oct 16;20(20):5123.

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