| General Information of MET (ID: META00782) |
| Name |
Vanillic acid
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| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
3-Methoxy-4-hydroxybenzoate; 3-Methoxy-4-hydroxybenzoic acid; 4 Hydroxy 3 methoxybenzoic acid; 4-Hydroxy-3-methoxy-benzoate; 4-Hydroxy-3-methoxy-benzoic acid; 4-Hydroxy-3-methoxybenzoate; 4-Hydroxy-3-methoxybenzoic acid; 4-Hydroxy-m-anisate; 4-Hydroxy-m-anisic acid; Acid, 4-hydroxy-3-methoxybenzoic; Acid, p-hydroxy-m-methoxy-benzoic; Acid, vanillic; Acide vanillique; Protocatechuic acid 3-methyl ester; Vanillate; Vanillic acid; p Hydroxy m methoxy benzoic acid; p-Hydroxy-m-methoxy-benzoic acid; p-Vanillate; p-Vanillic acid
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| Source |
Food;Yeast Metabolite;Food additives;TCM Ingredients;Ferulic;acid;Microbial; Herbal Ingredients In-Vivo Metabolism
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| Structure Type |
Benzoic acids and derivatives (Click to Show/Hide the Complete Structure Type Hierarchy)
Benzenoids
Benzene and substituted derivatives
Benzoic acids and derivatives
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| PubChem CID |
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| HMDB ID |
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| Formula |
C8H8O4
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| Structure |
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3D MOL
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2D MOL
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Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
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| KEGG ID |
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| ChEBI ID |
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| FooDB ID |
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| ChemSpider ID |
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| METLIN ID |
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| Physicochemical Properties |
Molecular Weight |
168.15 |
Topological Polar Surface Area |
66.8 |
| XlogP |
1.4 |
Complexity |
168 |
| Heavy Atom Count |
12 |
Rotatable Bond Count |
2 |
| Hydrogen Bond Donor Count |
2 |
Hydrogen Bond Acceptor Count |
4 |
| Function |
Vanillic acid is a phenolic acid found in some forms of vanilla and many other plant extracts. It is a flavouring and scent agent that produces a pleasant, creamy odour. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin (J Biotechnol 1996;50(2-3):107-13). Vanillic acid, which is a chlorogenic acid, is an oxidized form of vanillin. It is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid is a metabolic byproduct of caffeic acid and is often found in the urine of humans who have consumed coffee, chocolate, tea, and vanilla-flavoured confectionary. Vanillic acid selectively and specifically inhibits 5'nucleotidase activity. Vanillic acid is a microbial metabolite found in Amycolatopsis, Delftia, and Pseudomonas.
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Regulatory Network
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Induced Change